Using previously genotyped controls in genome-wide association studies (GWAS): application to the Stroke Genetics Network (SiGN)

Genome-wide association studies (GWAS) are widely applied to identify susceptibility loci for a variety of diseases using genotyping arrays that interrogate known polymorphisms throughout the genome.A particular strength of GWAS is that it is unbiased with respect to specific genomic elements (e.g., coding or regulatory regions of genes), and it ha

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Understanding heat tolerance in vegetables: Physiological and molecular insights, and contemporary genomic approaches for enhancing heat stress resilience

The increasing threat of heat stress in agriculture, fueled by the relentless rise in global temperatures, presents a formidable challenge for vegetable crops.High-temperature stress instigates intricate morphological, anatomical, and physiological changes in vegetables, resulting in a noticeable decline in yield and an overall compromise in qualit

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